In the beginning of the movie, news of UFO sightings around the world appear.

Jack Bruno (Dwayne Johnson) is a cab driver in Las Vegas, who is picking up and dropping off passengers to the UFO convention at the Planet Hollywood Casino and Hotel. One of his passengers is Dr. Alex Friedman (Carla Gugino), a failed scientist who is giving speeches about legitimate scientific theories of UFOs and outer space.

The next day Bruno is approached by two large men telling him that Wolff would like to see him. After fighting them, Bruno drives off, later noticing two children, Sara (AnnaSophia Robb) and...