In some way, they should end with the line "We've got work to do."
Like at the end of the Pilot and All Hell Breaks Loose Part 2.

I agree with Samsgirl, Love that line and it would make be all like awww*sob sob* thats soo cute*sob sob* I will miss them so much *sob sob* WAAAAAA *sob sob sob sob sob sob sob sob sob sob sob sob sob sob sob sob sob**

=D yes! Dean shall sayyy "we've got work to do" <3

I think it should be a classic Dean one liner or joke that's hilarious!

to me it all really depends on who says the last line this season :)

I would like Dean to have the last line. Something Dean-ish like "We've got work to do" or maybe something brotherly to Sammy. I don't know I'm sure I'll be happy with what ever Kripke has got planned. (Well as long as its Supernatural-y and not completely random!)

loool "We've got work to do" would be the best I guess^^

<Insert awesome speech here>
Dean: Bitch.
Sam: Jerk.
END

That would be kind of funny... Haha. Also the "we've got work to do" would be a very nice, nostalgic touch too. Just something that's "them", nothing random. To be honest, I don't mind what they say, anything that comes out of those mouths is more than worth loving! ;)

something that's funny and goes with Dean's personality
or what Kastielle just said :D

DEAN SHOULD SAY TO SAM WHERE MY PIE

yep ^^ pie its awesome one

I hope they´ll say `We´ve got work to do` but together at the same time. Or maybe a combination of all the great ones, ´We´ve got work to do´, something with pie and bitch...jerk.

Sam ´There are 500 pies who´ll take over the world if we don´t eat them all´
Dean ´We´ve got work to do Sammy´
Sam ´But I´ve already eaten all the apple pies´
Dean ´Bitch´
Sam ´Jerk´

But seriously as long as it isn´t some random line but something that´ll remind me of how great this show was and how much I will miss it it´s fine by me.

Dean to sam: We did it Sam... Now lets get me some pie.! :D
Good question. I don't know if i want it to be a funny ending or an emoutionel yet. We'll just have to see. I can't wait. Hope there is a season 6!

"Bitch." - "Jerk."
Because that's just a classic. ♥

Here's my idea:

Dean: "We're brothers, Sammy. Nothing can ever change that. Nothing."
Sam: (smiles) "It's Sam."
Dean: "Bitch."
Sam: "Jerk."
(both smile)
Sam and Dean: "We've got work to do."
(both get in the car at the same time and drive away)

It depends on how they end the series. I've decided that I would totally be okay with them ending it with Dean/Sam's deaths if they die hunting evil and protecting people in which case someone like Chuck or Castiel should say something awesome and poetic about the brothers.

If they end it with them "going off into the sunset" continuing to fight the good fight, so to speak, I think it should be Dean. I like, "We've got work to do." or something along those lines. I liked that one episode, I think it's What Is and What Should Never Be, where Dean is asking his Dad's grave (in AU) why they have to be the ones to save the world and later Sam tells him it's worth it. Maybe Dean could say it's worth it. Or something funny. I'm really not sure who should say the last line, but if our boys are still fighting, I like the idea of Dean saying it. Or them saying it together...ahhh I'm so torn! lol I don't even want to think about what the last line of my show could be! :(

We have a work to do :-D