I think that Peyton will die, the baby will die and then Lucas will kill himself. I know that sounds extreme, but look at this...neither one of them are coming back for season seven. There has to be a good reason.
i think that with out lucas in the show its a screw up lucas has been in the show fom day one and peyton is a big part of the show and brooke would not be acting as fine as she is in season 7 so i think they are okay they are just holding back on how payton and lucas are doing cause they want to scare the viewers they will most likely have them in the season8 and say the went traveling around the world or something and left tree hgill cause it was too much drama.