I feel sort of strange picking Cameron for this, but I think it's fitting. I can think of an instance where each of the other characters has asked for help (even House will go to Wilson for help if things get bad enough), but I can't really think of any for Cameron.

^^hhhhmmm well she may not have asked for help, but she certainly reaches out to people and is more willing to help herself than most of the characters. "Saviors" sticks in my mind for that.

I'd say Foreman, because it seems that he's even harder to break than House and wouldn't even talk to 13 in "Simple Explanation".

I'd say Cuddy would be next, Wilson forces himself on her to help her when she needs it. But even when she did ask for help they're either because of default (House finding out about the fertility injections) or because its not very serious (Wilson helping her pick out a baby crib). When its very serious, she tells no-one.

But I still stand by Foreman as the most unlikely to ask for help.

The obvious would be House, but Wilson I don't think can ask for help; since he always makes sure that there is no problem to begin with.

Cuddy can ask for help (IVF injections, Cameron replaceing her for an episode...etc)

xoxo

Definitley house.

and Cuddy...