1. Captain Hook and Ringmaster: Captain Hook would be cast as The Ringmaster because of their black mustaches. Okay maybe The Ringmaster from Dumbo would of have been a better fit.
2. Dr. Facilier and Dr. Doom: Dr. Facilier would be cast as Dr. Doom, because they're evil doctors who hire various villains to help him in his plan.
3. Kim Possible and Black Widow: Kim Possible would be Black Widow because she would be the gadget handy type much like Black Widow.
4. Shego and Mystique: Shego would be Mystique because she would be an evil equivalent to Kim Possible much like how Mystique is an evil equivalent to Black Widow.
5. Yokai and Mysterio: Yokai would be cast as Mysterio because they have no face underneath their disguise.
6. Xanatos and Professor X: Xanatos would be cast as Professor X because they're alike in a way (Xanatos eventually becomes a friend to Goliath and Professor X is constantly looking for new students for his academy)
7. Hans and High Evolutionary: Hans would be The High Evolutionary because they only pretend to be good when really they're evil.
8. Hiro and Iron Man: Hiro would be cast as Iron Man because they dress in similar armor.
9. Flynn and Wolverine: Flynn would be Wolverine because they're known for having dark hair.
10. Frollo and Grandmaster: Frollo would be Grandmaster because they have white hair.
11. Megara and Black Cat: Megara would be Black Cat because it's hard to tell with them whether they're working with the good guys or the bad guys.