Alone, although Spike/Buffy is my second favourite couple.

SPIKE&BUFFY FOREVER!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!

With Drusilla... such badasses!! Nothing beat season 2 Spike <3

With Buffy he had some of the best character development out of the whole show.
Everyone who thinks that he'd be better off like he was in season 2 really aren't thinking things through. For a start if he'd stayed the 'big bad' Buffy or one of the scoobies would have HAD to kill him. Secondly seeing no change or development in a character (no matter how brilliant) will eventually get boring. And thirdly how is it fair to want Spike and Dru together? Dru only hurt Spike by sleeping around and Spike only hurt Dru by loving Buffy more, having them together just seems cruel.

Spuffy <3

i agree with goodbyemra not to mention she cheated on him with angel multiple times and he is the one of the most interesting characters he got a soul for her and she became a better fighter and instead of killing someone and changing her beliefs with spike she cared for everyone and he always was honest about who he was with her and the speeches he has made about you just have to melt. they make each other better and stronger not to mention he helped saving the world many times without a soul and they look so cute together.

Spuffy forever<33