So i have seen this game on so many these spots and i figure lets try it out for Supernatural.
So how this game is played is the first person starts with something that is related to Supernatural that Starts with the letter A.
The next person relates something starting with the letter B. And so on and so on. When the letter Z is reached, the next person starts with A again. Avoid Repeats. Now on most of these spots they only get to letter E so lets attempt to get totally through.

I'll Start...

A: Ackles (Jensen)