LuthorCorp is an extensive billion-dollar corporation founded and run by Lionel Luthor. He started the company with insurance money he received after his parents were killed in a tenement fire. LuthorCorp originally specialized in the manufacture of pesticides, fertilizer, and other agricultural products.

LuthorCorp Plaza is the central building in Metropolis where business meetings and work is conducted. It is located next to the Daily Planet headquarters.

As a world leader in biotechnology and related industries, LuthorCorp maintains a unique combination of business, financial flexibility and global growth opportunities. LuthorCorp's brands touch more than a billion consumers each month. The new pesticides created in their laboratories have dramatically lengthened harvesting periods. Their farming equipment has revolutionized crop gathering machinery and when the fruits of the earth arrive on the dinner tables of the world, their innovative preservatives and packaging ensure that their nutritious value remains good far longer than their competitor's products.

The areas in which LuthorCorp directs its energies would be more accurately defined as biotechnology. The company is a frequent bone of contention between Lionel and his son Lex; the fact that their relationship is already strained makes their chess game over LuthorCorp even more intense. As of 2006, Lex is running the company, having banished his father from it; however, Lionel arranged a counter-coup, heading a consortium known as Apex to try and buy out the company from Lex. He was unsuccessful, but Lionel was brought back and now serves as an outside adviser of LuthorCorp.
LuthorCorp also owns the Metropolis Sharks professional football team.