Make your own Mane 6 using any characters.

Discord, King Sombra, Trixie, Queen Chrysalis, Nightmare Moon, Flim and Flam.

Oh yeah villains.

Trixie=Twilight Sparkle
Amethyst star=Rarity
Carrot top=Applejack
Rose=Pinkie pie
Daring do=Rainbow dash
Cheerilee=Fluttershy

Lyra, Dr. Whooves, Octavia, Vinyl, Derpy, Cloudkicker

Derpy, Dr. Whooves, Octavia, Lyra, Bon Bon, and Vinyl

Octavia, Screwball, Royal Ribbon, Quick Fix, Dust Devil, and Starsong / Sugar Apple. And because I spent too much time finding the last four, I need to write about these six.

Applebloom, Sweetie Belle, Scootaloo, Babs Seed, Twist, and Dinky.

princess Celestia, Nightmare Moon, Rainbow Dash, Princess Cadence, Twilight Sparkle, and Pinkie Pie.

Trixie, Lyra, Fluttershy, Cheerilee, Rarity, and Vinyl Scratch

me as twilight alexia as rarity saya as rainbow dash
lily as fluttershy shiraz as applejack haylee as pinkie pie

Discord
Trixie
Rose
Carrot Top
Vinyl
Derpy

Night Glider= Rainbow Dash

Party Favor=Pinkie Pie

Moondancer= Twilight Sparkle

Braeburn= Applejack

Treehugger= Fluttershy

Coco Pommel= Rarity

Oh... can i make more than one group?
Background 6: Derpy Hooves, Time Turner, Vinyl Scratch, Octavia Melody, Lyra Heartstrings, Sweetie Drops
Key 6: Discord, Seabreeze, Silver Shill, Cheese Sandwich, Spitfire, Coco Pommel
Reformed 6: Princess Luna, Discord, Sunset Shimmer, Trixie, Gilda, Babs Seed
Villainous 6: Nightmare Moon, Discord, Queen Chrysalis, King Sombra, Lord Tirek, Starlight Glimmer
Royal 6: Princess Celestia, Princess Luna, Princess Cadence, Twilight Sparkle, Shining Armor, Prince Blueblood

Derpy
Doctor Whooves
Octavia
Vinyl Scratch
Luna
Roseluck