PI House!

What are the real effects that vicodin has on House? Are these effects only physical or do they go beyond that? Could they have somewhat changed his personality, even just a little bit?

I watched the episode "Need to Know" (the one after House kissed Stacy, when at the end of the episode he ends up driving her away) for the first time like 4 months ago (got hooked with House just this year) and I didn't give this whole House/Stacy situation a lot of thought, it was fun but I wasn't that interested in the ship.

But the plot with Stacy kind of surprised me, because while I was watching the first...

House Season 1 Episode 7: Fidelity

Full Recap

After a morning jog with his friend, a man named Ed returns home to find his spouse sick in bed. Elyce has remained there for days. At the hospital, Cameron tells House that the patient has been sleeping 18 hours a day, but the tests don't reveal anything.

House and his team go through the possibilities -- Depression? Parasites? House orders new blood work and another MRI. After more testing, Elyce is told that there is no answer to her neurological problems. She goes into seizures.

House starts to suspect breast cancer. He also inquires about Elyce's...

The next morning was like before. Things change since they decided to go with the flow last night. Cuddy was up and was closing the last button on top of her blouse. She wasn’t looking at House who was seated on bed with only a blanket on. He, too, wasn’t looking at her. He ran a palm on his hair and finally got the courage to look at her.
House: I’m sorry for what had happen…
Cuddy: <smirk and looked at House> Knock it off… It wasn’t your fault… We both wanted it…
House said nothing as she went out the room to prepare their breakfast. He hated himself for what he did, for...