Higashi no Eden/Eden of the East.
link
It's in both sub and I believe dub, too. There's 1 or 2 movies that go along with it as well. I can't remember, though, since it's been a while since I last watched it.
Genre: Action, Comedy, Mystery, Drama, Romance, Sci-Fi, Josei
Episodes: 11
Type: TV Series
Age Rating: Teen +17
There's also Welcome to the NHK. It doesn't say it in the genre, but it can be kinda ecchi-ish here and there, but not to the point where it's overbearingly annoying.
link
Genre: Comedy, Romance, Slice of Life, Psychological
Episodes: 24
Type: TV Series
Age Rating: Teen +17
Space Brothers isn't exactly romantic, but you can tell that the main characters has feelings for this one girl and he'll often blush and whatnot and so will she. You know, like anime characters do. It also doesn't say there's comedy, but I for, find scenes here and there to be funny.
I still have yet to finish it, though, since it, is, or rather, was, ongoing. There's around 20 or less episodes I stopped watching for a while there since I got tired of waiting each week.
link
Genre: Sci-Fi, Space, Slice of Life, Seinen
Episodes: Unknown
Type: TV Series
Manga: Read Uchuu Kyoudai Manga Online
Age Rating: Everyone
Sorry if none of these are what you were looking for, or if you've already seen them, but hopefully someone will be interested, and if not, oh well then. xD