Are there any disabled characters in anime? Or characters with a limiting illness?

One That Comes to mind right now is Nunnally Lamperouge From Code Geass,she is blind and she's Paralyzed..but it goes all the way her when her mother "passed",she was paralyzed Due To Bullet Wounds and Blind due to psychological trauma,It's extremely sad to me T.T

Hm... I have a feeling someone's gonna say Ed with his missing arm and leg and Alphonse with his missing body, so I'll do something unique! Non-chan from Ojamajo DoReMi showed up in one episode of the last season and died of cancer... T~T I cried! Especially because Doremi helped Non-chan's mother cheer up... Non-chan's mom had promised to have a snowball fight with her the moment her cancer was cured, and Doremi offered to have a snowball fight with her in Non-chan's place, and the two of them had a snowball fight while laughing and crying... *sniffle*

Don't know if Mariko counts for handicap but she can't walk on her own because so many vectors weigh her down and not to mention she has a fake arm from when the scientist blew it off with one of the many bombs implanted throughout her body from when she was a baby.

she had trouble with her eyes until she got surgery in season 2 of yugioh

Sylvette can't move her lags since she was born. But,she can use the wheelchair really good.

Uhm, this wasn't like a lifelong thing and it was temporary (but wouldn't have been if she had not been healed by the Death Stone). Yomi was stabbed in 108 places by needles tearing ligaments(?) and making her 98% disabled aside from her head/neck and her hands. She moved her arm a little once but it wasn't something terribly significant.

Im gonna say toph

random but to me her song is "I will not bow"

Ayase shinomiya from guilty crown
She can't walk but she still is a great fighter with her wheelchair, she did knock out the main character shu with just one blow.

Eriru from Pichi Pichi Pitch has something called multiple personality disorder. It's when somebody has more then one different personality which are very different to eachother, like different likes, dislikes, beliefs, memories.

Sound MariefromD.Gray-Man is blind

Yui can't move her legs

.. Nagisa Furukawa has this strange illness.
She's not really handicapped, but she gets very sick almost often..

in air tv when misuzu makes friends with people she gets really sick and cant walk .... then somthing else happens but i dont want to spoil it

Well Seiichi-kun from Prince of Tennis was diagnosed and treated for Guillain-Barre syndrome.

*Guillain-Barre syndrome is a serious disorder that occurs when the body's defense (immune) system mistakenly attacks part of the nervous system. This leads to nerve inflammation that causes muscle weakness.

Aoi Hyuga from Gakuen Alice. She was blind and had lost memory of her family due to an axident that made her loose control of her fire alice. She also got a very high fever that had an abnormal temperature. It was caused by that A**hole Persona.

kimimaro had a fatal sickness on naruto

I really don't know if you can call Nurarihyon from Nurarihyon no Mago disabled if he had his heart ripped out. . .
I think that's limiting since, well, he had his heart ripped out, it greatly decreased his lifetime. (By the way he already looks old even though he's still like, around 500 years old- which is young for someone like him.)
Oh, and before you ask how he is still living after having his heart ripped out, it's because he's a yokai, a Japanese supernatural creature. (Which probably also explains his, err, head shape.)

Hehe, the first person that came into my mind when I saw this question was Talbot from Katekyo Hitman Reborn:

Kana is a magic user who escaped with Kuroha Neko at the beginning of the story. In the process of becoming a magician she became paralyzed when they implanted her "harness". She can only drink and move her left hand. She can't speak but uses a device which synthesizes the voice.

Rentaro Satomi from Black Bullet lost his right limbs and left eye when he protected Kisara from Gastrea in their childhood.

Shishio from Rurouni Kenshin is covered in burns, so he doesn't have sweat glands and will overheat and die if he does something strenuous for too long.

Also one of my favorite anime villains.

Johnny Joestar is crippled in the legs, and he's my favourite Jojo.

Itachi Uchiha (Naruto Shippuden)

Itachi's illness is hemoptysis. The hemoptysis is, more likely than not, a result of diffuse alveolar hemorrhage. This is a classic symptom of MPA when it presents with pulmonary manifestations. There is also shortness of breath, and coughing.

Death the Kid from Soul Eater has OCD, if that counts...

But ok, my actual answer is Takuma Hirose from H2O: Footprints in the Sand. He's blind in both eyes. Real cutie though!